Epigenetics & Genetic Mutations

Epigenetics & Genetic Mutations Photo
A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people. Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes. Gene mutations are of two types Hereditary mutations and Acquired (or somatic) mutations. The former inherited from a parent and are present throughout a person’s life in virtually every cell in the body and the latter occur at some time during a person’s life and are present only in certain cells, not in every cell in the body. Genetic alterations that occur in more than 1 percent of the population are called polymorphisms. They are common enough to be considered a normal variation in the DNA. Polymorphisms are responsible for many of the normal differences between people such as eye color, hair color, and blood type.

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