A gene regulatory
network (GRN) is a collection of molecular regulators that interact with each
other and with other substances in the cell to govern the gene expression levels of mRNA and
There are primarily two ways that networks can evolve, both of which can occur
simultaneously. The first is that network topology and the second way
networks can evolve is by changing the strength of interactions between nodes.
Another widely cited characteristic of gene regulatory network is their
abundance of certain repetitive sub-networks known as network motifs. The enriched
motifs have been proposed to follow convergent evolution. Regulatory networks
allow bacteria to adapt to almost every environmental niche on earth. Formally most
of the approaches are similar to an artificial neural network.